Mammographic mass detection with a hierarchical image probability (HIP) model

We formulate a model for probability distributions on image spaces. We show that any distribution of images can be factored exactly into conditional distributions of feature vectors at one resolution (pyramid level) conditioned on the image information at lower resolutions. We would like to factor this over positions in the pyramid levels to make it tractable, but such factoring may miss long-range dependencies. To x this, we introduce hidden class labels at each pixel in the pyramid. The result is a hierarchical mixture of conditional probabilities, similar to a hidden Markov model on a tree. The model parameters can be found with maximum likelihood estimation using the EM algorithm. We have obtained encouraging preliminary results on the problems of detecting masses in mammograms.